If you want it to auto burst i.e. Bestial Wrath for BM then you have to enable it in the settings the way you want it to or just use the burst target hotkey.
For Tranq Shot the default settings are wrong. It's 80/80 which means he will only tranq the target for high priority buffs like bop, sacrifice and alter time if he is above 80 focus and your target is above 80% health.
I suggest setting it to 20/0 or something more fitting. If you want to add other spells you have to use the custom spell ID list for that