I'd break it up by ink type or a batch load / ink retrieval from storage phase, and for popular glyphs, make 3 of each.
Popular, being determined by wowuction sales info, or preemptive patch notes / PTR notes.
creating ~345 glyps will use around 1000+ inks not easily stored. And you'll most likely need 2 to 5 of each popular spec -> respec if you're very selective.
On patch day, dont use prof buddy (likely will not load), use a posting addon, manually adjust the TOC version value so you don't need to patch early to get it working.