I would suggest using the release version first (so DB team will provide support if there are issues), but if a plugin or feature requires you to use a Beta build, then thats the only time you use the beta build.
First step of Demonbuddy support (assuming you provided a log adequately):
1) If using release version of DB, "please use Beta version and let us know"
2) If using Beta version of Db, "please use Release version and let us know"