Well, there's a baseline in players' reaction to other players depending on the population type:
High: people are highly indifferent to each other. Farming zones are always crowded, questing zones aren't empty and popular grinding spots are rarely left alone.
Low: the opposite. Someone might have been farming the whole zone alone before you showed up. Someone might've been questing all alone before you showed up. Someone might've had a spot all to himself to grind before you showed up. You immediately draw their attention.
That being said, I'd rather bot at High/Full realms, but anything is fine if you supervise your bots and/or configure plugins to react adequately to being stuck/getting whispers.