Major hint to all....
Always, always, always:
1: Install a new version of DB in a new, clean empty folder. Do not use the auto-updater, and do not simply copy-replace a downloaded new version over your old DB folder.
2: Check all of your plugins for any updates - see if you have any outdated plugins that need downloading fresh.
3: Re-configure any plugins and DB settings after a new install, since it will all reset to default.
4: If you are using a plugin which hasn't been updated in 2+ weeks, and you have problems, try removing that plugin and see if the problems go away - some people still use very old plugins that haven't been updated in weeks and aren't even needed anymore.
If you follow these steps, while I can't guarantee you'll magically make DemonBuddy be perfect and Diablo 3 never crash, you will minimize your problems, and rule out a lot of possible issues.