Sure, there is a WD speed build that you use wormwood in the cube and that passively casts Locust Swarm, so if you use Vile Hive off hand and you rune Searing Locust's then you passively cast this on everything.
I'm already running an LoN Searing Locusts build & it works just fine with Wormwood cubed & no changes to the existing Trinity. I haven't attempted a T10 with it but then I generally just stick with T8's for farming anyway. This is the version of it that I run http://www.diablofans.com/builds/68598-ptr-2-4-witch-doctor-lon-searing-locusts-build so it's casting Haunt. You just run around & everything dies from the Locust Swarm ticks, it's the easiest to play build ever.
Yeh its the one bregov linked. It uses Aquilia's so its best you dont cast Locust Swarm you can just run around in T10 and everything dies.. this is a end game farming build though.