There hasn't been a really succesful mmo that tries to be completely fresh ever since wow (and obviously wow wasn't completely revolutionary as some people who were actually playing mmos at the the time will claim. Wow happened to be at the right time on the right place with the right market.
That being said, wow is actually bleeding players in occidental markets at a huge rate. Blizzard inflates user numbers with stuff like 1 free month players, and the asian market that saw it introduced a few years later, so the userbase there still have some interest in playing same thing over and over. And if blizzard really wants to keep the golden chicken, they'll have to upgrade it....so there will have to be a wow2.
If titan is released in the time frame between the virtual "end" of wow1, and the release of the upgraded wow2 (I don't think titan is wow2, they have denied that often but I won't trust a word they say again) it could be hugely succesful.
Only time will tell. Yet I agree the decision of creating a bot or not by the buddys shouldn't be strictly taken by the game sales, since that would mean the bot wouldn't be available for the first months while it is on development, and therefore the best time for botting for profit would be lost.
Anyway, titan was expected to be released by the end of next year (2014) , and that's even considering no delay would come which is hugely unlikely. We botters should be looking for another game to bot in the meantime, methinks.