Figured it out (at least for me)
After spending hours trying, I finally found the combo that solved this.
DB would crash every 1-3 mins of use. Keep in mind, everything worked perfectly before 2.0.4 Here are the things I tried:
Reinstalled (to a fresh directory) with: Beta.zip
New release (352).zip
New release (352) installer
Older version and patched
Older version and copypasted new version on top
Used trinity 1.8.15/17
Used trinity 1.7
Used BuddyWizard
Tried different profiles
Run everything in administrator/windowed mode
Lowered tick rate to 6, also tried raising to 15
Tried different characters
Multitudes of different video settings
System Restore to a point when DB was working
Submitted logs/scoured forums
Probably other things I'm not remembering
It just started working after I uninstalled/re-installed D3, and then installed the .zip release of DB. Haven't crashed in 2 hours (however battle.net is still losing connection, but I think that's a Blizzard issue, not a DB one.)
I have no idea why it works now and it didnt before, but I hope this helps someone.