it may be a few things. it could be a corrupted cache.---delete the cache folder, you will find it in the HB folder.
it may be a quest that is old and needs to be updated.---shut down honorbuddy and do a couple quests to get past the bump.
if you are still having issues, it may be a corrupted file in honorbuddy itself.---download the zip file and extract into a new folder. do not install in the original folder. run HB with no plugins. if you have no issues, you may then load your favorite plugins and proceed.
these things happen frequently while you are learning how honorbuddy runs on your comp. most people have no issues, but there are some that are accident prone.
after a couple months, you will be troubleshooting these issues and have near to no downtime at all.
here are a few tips to get you started. if you have an issue. search the forums for similar issues. such as your issue sounds like a profile issue. you would go to the profile pack thread and read the last couple pages. if you dont see it there, make a post describing your issue and post your log. you find instructions on where to find and how to post your log in the link below. after that, go to the support section. repeat your post there with a detailed description of your issue, what you may have done to fix it, and of course, your log.
this allows staff members and developers to help you quicker. a log is very important because it might help developers find the 'bugs' faster by comparing other logs to yours. every little bit helps. Your log may be the one that helps them fix the issue.