About Proxy that's risk for sure I have experience once about blacklist IP and autoban all character on low level with same IP.
a lot of my bot with debuff get ban and not for some.
I don't think all player will get ban just because debuff if never use bot.
before this suspect debuff user never get ban because they ignore, I saw someone bot farm mob at the same place or trade run bot with debuff in full month without ban.
but for player using bot if you get debuff it's unsafe now because that's mean your character will be check by gm.
maybe check from Log but seem they have some way to checking bot right now.
I still focus about grinding or quest but I'dont know yet for the real thing how they can detect.
but I want to say about risk
For example
in bot auto quest will have the same pattern such as do quest with same step 1,2,3,4,5,...
need to done quest 1 to do quest 2 or done quest 2 to do quest 3 bla bla bla... it will not random to do quest and also skip some hard quest.
on quest pet bot alway select same pet not random pet.
overarcheive all time or no overarcheive at all.
when reach to xx level will equip item or remove item.
Up skill with same pattern on each class
stuck in some area
If you use grinder bot to level (without quest) that's maybe risk because the most level by quest.
or farm mob to find coinpurse in all day or many hour everyday maybe unsafe because normal player behavior have many thing to do such as CR, GR, Trade Run, Fishing, Planting / Harvest ,Craft Item or do Event not just farm mob.
my friend get ban on 3 account with character level 55 Proficiency Larceny 180k and don't have other Proficiency over 10k that's risk for sure.
nothing safe if you just bot without monitoring because if someone around you and you don't have any action response like normal player that's maybe cause to report and get ban in finally.