в профиле тоже можно начиная с 283 версии
Changelog .283
"monsterPower" added in the GameParams so a profile can override the value in the settings, example:
<GameParams quest="87700" step="-1" act="A1" difficulty="Inferno" resumeFromSave="False" monsterPower="5" />
еще можно в релогере YAR