What I mean to say is, if you need to pause HB in a hurry as in a GM poofs out of nowhere calling your name. Is there a key stroke that can actually paud the bot until it is safe?
Alt+tab then click stop? It takes all of 2 seconds.
As for answering your question, I don't believe there is a hotkey, but some botbases have hotkeys, Enyo for example has a customizable setting for pause, which I use all the time.