Traditional ore and herb markets have partially collapsed on many servers as raid guilds stop in prep for MoP. Even the ore shuffle has lost much of its viability lately, at least on my server. Unless you really need the money now, one recommendation would be to create a stockpile on items that will be in high demand come MoP as new and returning players buy mats to level up professions.
Ore from Outland is a particularly valuable commodity right now. The prices on Saronite, etc are already incredibly high on my server. While the demand right now is mild, meaning I wouldn't flush it with 100 stacks on a single night, the demand will only rise as MoP comes so now is a good time to get ahead of the curve.
Another avenue would be to try fishing. The market for fish, especially the mats required for Seafood Magnifique Feast has still remained fairly strong on my server, though demand a bit down due to the wane of this expansion. So you might find it profitable to dip into this market a bit as well. Fishing in pools does not require a certain fishing level, so initial investment would be minimal.
Overall, markets are certainly shifting like they do before every expansion. Try to use this to your advantage.