I had a simular issue when I used one of the older quest plug in. Was lagging it so hard the program was super slow to respond. Not sure how to fix it. make sure your move button is not on mouse button.I will just chime in to say that I encountered this issue once or twice BEFORE this update so it's nothing new.
The mouse gets stuck in game and no matter how many times you click stop on the bot it doesn't stop and you gotta restart PoE