It can be definied in the Profile you are using to Kill them, or not to. It will overwrite ur Settings in the Options.
U dont want to disable this Feature, trust me. Its not good to have it off in like 95% of the time, since the hotspot is just one or more small points, where he only kills mobs in the pull radius if u have this turned off, meaning he is only klling mobs if he is exactly at the Hotspot point.
Also, if u go into a cave or anything u will have 20+ mobs at your butt killing u before u even get to the Hotspot inside of it.
I Know, at some points its pretty annoying, but if the Profilecreater meant it to be checked, it should stay checked.
Hope i could make this a bit clear.
Greetings