I only do GR on my sader, using Flashfire for TX.
But I run with Ignore minions, packsize 4, checks removed from all avoidance.
That's basicly the only tweaks i've done. Doing 65 pretty easy. Do note however my paragon is fairly high, and do have decent gear.
50-55 should be pretty damn easy if you just have 6p and some of the loots required.
Ye for TX, is wizard a lot faster then crusader...clearing mostly in under 3min with flash build(WIZARD)...maybe you do it like kafflaff and use crusader only for grifts