no gathering sucks ass now (no flying mounts and prices falling day by day and the fact everyone has a bot), its all about running multiple garrisons now.... it will provide you with all the mats you will ever need AND allow you to bypass the time gate that is mat/gear creation. its about making end products now.
THE ONLY PEOPLE I KNOW MAKING 50-100K A DAY is the guys who have at least 6+ garrisons pumping out enchants, mounts,gear and most importantly cards right now. the gear thing will have to be rotational since the mats are largely bop but the cards and enchanting mats can be combined. their garrisons are churning out mats none stop basically. ANYONE WHO DOESNT HAVE MULTIPLE GARRISONS WILL BE GATED HARD
if you want to make long term investment than all your toons and garrisons will need to have enchanting, i expect cards and boe gears to be dead on dec 2nd. alchemy might make a return because i know how any guild worth a damn and raiders who want to boost epeen on dps meter will always willing to pay for flasks during raids. demand wouldnt be an issue because the supply is gated by time so even botters have to buy stuff if they want to equip min/maxing
with a bot it shouldnt take long at all to do so. also make mostly t2 garrisons w a few t3s since t3s are expensive, massing t2s yields the most returns
also i suggest you have a scribe and a tailor for bags because you will have a lot of toons to level.