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I certainly have not done any comparisons, so all I can offer is my experience.
So 10 days now after Season 5 start I have ancients in all but one slot on my WD and I'm farming GR63 now.
I mainly used the death's breaths I got from regular rifts together with ancient drops as I kept pushing the GR level higher. Obviously you should do the crafting intelligently, IE for WDs, mainly staff and mojo, that is, the ones that have the fewest legendaries, so your odds of getting the one you want go up.